Name : HIPPI Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2924428062
| Long name | HIPPI Primary Polyclonal Antibody |
| Also known as | HIPPI PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | HIPPI |
| Specificity | This is a highly specific antibody against HIPPI |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HIPPI |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Huntingtonâ, Polyglutamine expansion reduces the level of association between Hip-1 and Htt, The Hippi-Hip-1 heterodimer is a pro-apoptotic complex that recruits procaspase-8 and initiates caspase-8 activation, The human hippi gene maps to chromosome 3q13, thereby increasing levels of free Hip-1 that then can be the candidate protein Hippi (Hip-1 protein interactor), which may contribute to the neuronal cell death observed in individuals diagnosed with Huntingtonâ, which occur later in human life, &euro, &euro, &trade, &trade, 13 and encodes a 429 amino acid protein, Programmed neuronal cell death is a feature of neurodegenerative disorders such as Alzheimer's and Huntington's disease, s disease, s disease at the molecular and cell level is characterized by polyglutamine expansion of the protein huntingtin (Htt) that leads to apoptotis-mediated neurodegenerative loss of medium spiny neurons throughout the striatum |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CDNA FLJ10147 fis clone HEMBA1003369, DERP 8, DERP8, Dermal papilla-derived protein 8, ESRRBL1 protein, Esrrbl 1, Esrrbl1, Estrogen related receptor beta like 1, Estrogen related receptor beta like protein 1, Estrogen-related receptor beta like 1, Estrogen-related receptor beta-like protein 1, FLJ10147, HIP1 interacting protein HIPPI, HIP1-interacting protein, HIPPI, Hip1 Interacting Protein, Hip1 protein interactor, Huntingtin interacting protein 1 interacting protein, Huntingtin interacting protein 1 protein interactor, Huntingtin-interacting protein-1 protein interactor, Intraflagellar transport 57 homolog, Intraflagellar transport 57 homolog Chlamydomonas, Intraflagellar transport protein 57 homolog, MHS4R2, T 57, T57_HUMAN, Vestrogen related receptor beta like 1, Vestrogen-related receptor beta like 1, t57, Dermal papilla derived protein 8 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | HIPPI |
| Short name | HIPPI Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | HIPPI (Antibody to) |
| Alternative technique | antibodies |
| Identity | 17367 |
| Gene | IFT57 |
| Long gene name | intraflagellar transport 57 |
| Synonyms gene | ESRRBL1 |
| Synonyms gene name | estrogen-related receptor beta like 1 intraflagellar transport 57 homolog (Chlamydomonas) |
| Synonyms | FLJ10147 HIPPI MHS4R2 |
| Locus | 3q13, 12-q13, 13 |
| Discovery year | 2002-01-18 |
| GenBank acession | AK001009 |
| Entrez gene record | 55081 |
| RefSeq identity | NM_018010 |
| Classification | Intraflagellar transport proteins |
| Havana BLAST/BLAT | OTTHUMG00000159223 |