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HPV33 E6 Antibody

HPV33 E6 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameHPV33 E6 Primary Polyclonal Antibody
Also known asHPV33 E6 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenHPV33 E6
Specificity HPV58, This antibody will detect E6 in HPV33, and Alphapapillomavirus 9, This is a highly specific antibody against HPV33 E6
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range90-140/149
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human HPV33 E6 protein
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityVirus
Cross reactive species details Alphapapillomavirus 9, HPV58, HPV33
Background of the target antigen 31 and 33, Approximately 90% of cervical cancers contain HPV DNA of the high risk types, Binds double-stranded DNA, HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types, However, Human papillomaviruses (HPV) are small DNA viruses which infect epithelia of the skin and mucosa, Mutational analysis have shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function, Over 90 types have been identified and they mostly cause a variety of benign lesions such as warts and verrucae, The E6 protein is a transcriptional transactivator, The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, The specific interactions of the E6 and E7 proteins with p53 and pRB, This protein may be involved in the oncogenic potential of this virus (cervical neoplasia-associated virus), and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro, correlate with HPV high and low risk classifications, have been confirmed as agents which cause cervical cancer, notably types 16 and 18, respectively, some subtypes, Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names HPV33 E6 protein, HPV33-E6 protein, Human Papilloma Virus, Human papillomavirus type 33, Human papillomavirus type 33, Protein 33, VE6_HPV33, E6 protein [Human papillomavirus type 33]
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetHPV33 E6
Short nameHPV33 E6 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameHPV33 E6 (Antibody to)
Alternative techniqueantibodies

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