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LGR5 Antibody

LGR5 Antibody size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormPurified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenLGR5
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, FACS, IF, IHC, WB
Recommended dilutionsFlow Cytometry: 1:10-1:50, IHC (Paraffin): 1:10-1:50, Immunofluorescence: 1:10-1:50, Western blot: 1:1000
NotesTitration of the LGR5 antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis LGR5 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #O75473
PurityPurified
Description Expressed at the base of crypts in colonic and small mucosa stem cells, Expressed in skeletal muscle, In premalignant cancer expression is not restricted to the cript base, It may be an important receptor for signals controlling growth and differentiation of specific embryonic tissues, Overexpressed in cancers of the ovary, Stem cell marker of the intestinal epithelium and the hair follicle, Target gene of Wnt signaling, and various region of brain, colon and liver, placenta, spinal cord, LGR5/GPR49 is an orphan receptor
ImmunogenA portion of amino acids 238-270 from the human protein was used as the immunogen for this LGR5 antibody
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the LGR5 antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetLGR5
Short nameLGR5 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameLGR5 (Antibody to)
Alternative techniqueantibodies
Identity 4504
Gene LGR5
Long gene name leucine rich repeat containing G protein-coupled receptor 5
Synonyms gene GPR67 GPR49
Synonyms gene name G protein-coupled receptor 49
Synonyms HG38 FEX
Locus 12q21, 1
Discovery year 1999-10-22
GenBank acession AF062006
Entrez gene record 8549
Pubmed identfication 9642114
RefSeq identity NM_003667
Classification Class A orphans , G protein-coupled receptors
Havana BLAST/BLAT OTTHUMG00000169543

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