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MARCH3 Antibody

MARCH3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMARCH3 Primary Polyclonal Antibody
Also known asMARCH3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target Antigen37681
SpecificityThis is a highly specific antibody against 37681
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MARCH3
Gene ID number115123
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Involved in the pathway of protein modification, MARCH3 (membrane-associated ring finger (C3HC4) 3), MARCH3 functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and is thought to be involved in endosomal trafficking events, The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), also known as RNF173, is a 253 amino acid multi-pass membrane protein that localizes to cytoplasmic vesicles and early endosomes and contains one RING-CH-type zinc finger, the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s), Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names FLJ20096, MARCH-III, MARH3_HUMAN, March3, Membrane associated ring finger C3HC4 3, Membrane-associated RING finger protein 3, Membrane-associated RING-CH protein III, RING finger protein 173, RNF173, E3 ubiquitin-protein ligase MARCH3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMARCH3
Short nameMARCH3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name E3 ubiquitin protein ligase (Antibody to), membrane-associated ring finger (C3HC4) 3
Alternative techniqueantibodies
Alternative to gene target E3 ubiquitin protein ligase, MARCH3 and IDBG-39523 and ENSG00000173926 and 115123, MARCH3 and IDBG-644898 and ENSBTAG00000006797 and 520348, March3 and IDBG-148017 and ENSMUSG00000032656 and 320253, Plasma membranes, metal ion binding, this GO :0005515 and protein binding and molecular function this GO :0005764 and lysosome and cellular component this GO :0005768 and endosome and cellular component this GO :0006897 and endocytosis and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0016021 and integral component of membrane and cellular component this GO :0016567 and protein ubiquitination and biological process this GO :0016874 and ligase activity and molecular function this GO :0030659 and cytoplasmic vesicle membrane and cellular component this GO :0031901 and early endosome membrane and cellular component this GO :0046872 and metal ion binding and molecular function, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0008270: zinc ion binding and also this GO :0016874: ligase activity and also this GO :0046872: metal ion binding, this GO :0008270: zinc ion binding, this GO :0016874: ligase activity, this GO :0046872: metal ion binding, membrane-associated ring finger (C3HC4) 3
Identity 28728
Gene MARCH3
Long gene name membrane associated ring-CH-type finger 3
Synonyms gene name E3 ubiquitin protein ligase , membrane-associated ring finger (C3HC4) 3 membrane-associated ring finger (C3HC4) 3
Synonyms MGC48332 MARCH-III RNF173
Locus 5q23, 2
Discovery year 2005-01-26
GenBank acession AF055007
Entrez gene record 115123
Pubmed identfication 14722266 8619474
RefSeq identity NM_178450
Classification Membrane associated ring-CH-type fingers Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000128968

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