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MARCH8 Antibody

MARCH8 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMARCH8 Primary Polyclonal Antibody
Also known asMARCH8 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target Antigen39508
SpecificityThis is a highly specific antibody against 39508
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MARCH8
Gene ID number220972
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Expressed in a variety of tissues, MARCH8 (membrane-associated ring finger (C3HC4) 8), MARCH8 functions as an E3 ubiquitin ligase that is thought to regulate immune responses by promoting the ubiquitination and subsequent degradation of target proteins, Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation, also known as MIR or RNF178 (RING finger protein 178), including immature dendritic cells, is a 291 amino acid multi-pass membrane protein that localizes to vesicle membranes and contains one RING-CH-type zinc finger, such as B7-2 and CD71, The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Cellular modulator of immune recognition, E3 ubiquitin protein ligase MARCH8, E3 ubiquitin-protein ligase MARCH8, MARCH 8, MARCH VIII, MARCH-VIII, MARCH8, MARH8_HUMAN, MIR, Membrane associated RING CH protein VIII, Membrane associated RING finger protein 8, Membrane associated ring finger C3HC4 8, Membrane-associated RING finger protein 8, Membrane-associated RING-CH protein VIII, RING finger protein 178, RNF178, c-MIR, c MIR
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMARCH8
Short nameMARCH8 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMARCH8 (Antibody to)
Alternative techniqueantibodies
Identity 23356
Gene MARCH8
Long gene name membrane associated ring-CH-type finger 8
Synonyms gene MIR
Synonyms gene name E3 ubiquitin protein ligase , c-mir, cellular modulator of immune recognition membrane-associated ring finger (C3HC4) 8 membrane-associated ring finger (C3HC4) 8
Synonyms c-MIR CMIR MARCH-VIII RNF178
Locus 10q11, 21-q11, 22
Discovery year 2003-11-12
GenBank acession AL833316
Entrez gene record 220972
Pubmed identfication 12582153 14722266
RefSeq identity NM_145021
Classification Membrane associated ring-CH-type fingers Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000019345

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