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MMS19 Antibody

MMS19 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMMS19 Primary Polyclonal Antibody
Also known asMMS19 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMMS19
SpecificityThis is a highly specific antibody against MMS19
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range930-975/1030
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MMS 19
Gene ID number64210
Swiss ProtQ96T76
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen As part of the mitotic spindle-associated MMXD complex, FANCJ and RTEL1, In the CIA complex, Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription, via its role in iron-sulfur insertion into some component of the TFIIH-machinery, Key component of the cytosolic iron-sulfur protein assembly (CIA) complex
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names MET18 homolog, MMS19, MMS19 nucleotide excision repair protein homolog, MMS19-like protein, MMS19L, hMMS19, MET18
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMMS19
Short nameMMS19 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMMS19 (Antibody to)
Alternative techniqueantibodies
Identity 13824
Gene MMS19
Long gene name MMS19 homolog, cytosolic iron-sulfur assembly component
Synonyms gene MMS19L
Synonyms gene name MMS19 nucleotide excision repair homolog (S, cerevisiae)
Synonyms MET18 hMMS19
Synonyms name MET18 homolog (S, cerevisiae)
Locus 10q24, 1
Discovery year 2000-12-21
GenBank acession AF007151
Entrez gene record 64210
Pubmed identfication 11071939 22678362 22678361
Classification Nucleotide excision repair Cytosolic iron-sulfur assembly components
Havana BLAST/BLAT OTTHUMG00000018857

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