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MTMR14 Antibody

MTMR14 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameMTMR14 Primary Polyclonal Antibody
Also known asMTMR14 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenMTMR14
SpecificityThis is a highly specific antibody against MTMR14
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MTMR14
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen In these studies, In zebrafish, MTMR14 deficiency in mice leads to altered calcium homeostasis and muscle disorders (2), MTMR14 has also been shown to play a role in autophagy, MTMR14 inhibited autophagy and mutations of MTMR14 associated with centronuclear myopathy were also defective in autophagy inhibition, MTMR14 knockdown was shown to increase the number of autophagosomes, MTMR14 was localized to autophagic isolation membranes and early autophagosomes (3), Mutations in the MTMR14 gene have been associated with centronuclear myopathy (1), Vps34 (3), a process that is highly regulated by phosphatidylinositides through the type III PI3K, also known as Jumpy, is a myotubularin-related phosphoinositol-3-phosphate (PI3P) phosphatase (1), suggesting that its activity is associated with an inhibition of autophagy (4), Myotubularin-related protein 14 (MTMR14)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Egg derived tyrosine phosphatase homolog, FLJ11546, FLJ22405, FLJ46453, FLJ90311, HCV NS5A transactivated protein 4 splice variant A binding protein 1, HCV NS5A-transactivated protein 4 splice variant A-binding protein 1, MTMR 14, MTMR-14, MTMR14, MTMRE_HUMAN, Myotubularin related protein 14, Myotubularin-related protein 14, NS5ATP4ABP1, hJumpy, jumpy, C3orf29
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetMTMR14
Short nameMTMR14 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameMTMR14 (Antibody to)
Alternative techniqueantibodies
Identity 26190
Gene MTMR14
Long gene name myotubularin related protein 14
Synonyms gene C3orf29
Synonyms gene name chromosome 3 open reading frame 29
Synonyms FLJ22405 FLJ90311 hJumpy hEDTP
Synonyms name egg-derived tyrosine phosphatase homolog (Drosophila)
Locus 3p25, 3
Discovery year 2005-12-22
GenBank acession BC001674
Entrez gene record 64419
Pubmed identfication 15186772
RefSeq identity NM_022485
Classification Phosphoinositide phosphatases Myotubularins
Havana BLAST/BLAT OTTHUMG00000155111

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