Filters

NEDD8 Antibody

NEDD8 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameNEDD8 Primary Polyclonal Antibody
Also known asNEDD8 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNEDD8
SpecificityThis is a highly specific antibody against NEDD8
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NEDD8
Gene ID number4738
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Apg12 and Hub1, Cullins are subunits of an E3 ubiquitin ligase complex called the Skp1 /Cul1/Cdc53 F box (SCF), Examples of UBLs are SUMO, In contrast to UBLs, NEDD8 shows 80% homology to ubiquitin, Proteins of the second class include Parkin, RAD23 and DSK2, Rub1 (also called Nedd8), Rub1 and the corresponding human homolog NEDD8 are activated by the E1 ubiquitin activating enzyme UBA2, Rub1 modification may regulate SCF function or localization, The SCF promotes transfer of ubiquitin from a ubiquitin conjugating enzyme (E2) to the target protein, The best known targets of Rub1 modification are members of the cullin family, These proteins contain domains that are related to ubiquitin but are otherwise unrelated to each other, UDPs are not proteolytically processed or conjugated to other proteins, are designated ubiquitin domain proteins (UDPs), that forms isopeptide linkages between thio esters, ubiquitin-like modifiers (UBLs) function as modifiers in a manner analogous to that of ubiquitin, Ubiquitin like proteins fall into two classes: the first class
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names NEDD 8, Neddylin, Neural precursor cell expressed developmentally down regulated 8, Neural precursor cell expressed developmentally down regulated gene 8, Rub1, Ubiquitin like protein Nedd 8, Ubiquitin like protein Nedd8, NED8
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetNEDD8
Short nameNEDD8 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameNEDD8 (Antibody to)
Alternative techniqueantibodies
Identity 7732
Gene NEDD8
Long gene name developmentally down-regulated 8 , neural precursor cell expressed
Synonyms Nedd-8
Locus 14q12
Discovery year 1994-01-21
GenBank acession D23662
Entrez gene record 4738
Pubmed identfication 9353319
RefSeq identity NM_006156
Havana BLAST/BLAT OTTHUMG00000029325

Similar products

Subscribe to our Newsletter