Name : p150 CAF1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN3078300834
| Long name | p150 CAF1 Primary Polyclonal Antibody |
| Also known as | p150 CAF1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | p150 CAF1 |
| Specificity | This is a highly specific antibody against p150 CAF1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human p150 CAF1 |
| Gene ID number | 10036 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, Assembles histone octamers onto replicating DNA in vitro, CAF-1 performs the first step of the nucleosome assembly process, CHAF1A binds to histones H3 and H4, It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci (By similarity), The CCR4-NOT complex functions as general transcription regulation complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), a complex thought to mediate chromatin assembly in DNA replication and DNA repair, bringing newly synthesized histones H3 and H4 to replicating DNA, histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer, which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene, Core component of the CAF-1 complex |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | CAF, CAF 1, CAF 1 150 kDa subunit, CAF 1 subunit A, CAF I 150 kDa subunit, CAF I p150, CAF Ip150, CAF-1 subunit A, CAF-I 150 kDa subunit, CAF-I p150, CAF1, CAF1 150 kDa subunit, CAF1 p150 Subunit, CAF1 subunit A, CAF1A, CAF1A, CAF1A_HUMAN, CAF1B, CAF1P150, CAF1P155, CAF1P155, CHAF1A, Chromatin Assembly Factor 1 Subunit A p150, Chromatin Assembly Factor I, Chromatin assembly factor 1 subunit A, Chromatin assembly factor I 150 kDa, Chromatin assembly factor I 150 kDa, Chromatin assembly factor I p150 subunit, DCAF1, NURF150, Nucleosome Remodeling Factor 150kDa Subunit, P150, hp150, CAF-1 p150 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | p150 CAF1 |
| Short name | p150 CAF1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | p150 CAF1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 14101 |
| Gene | CNOT7 |
| Long gene name | CCR4-NOT transcription complex subunit 7 |
| Synonyms gene | CAF1 |
| Synonyms gene name | CCR4-NOT transcription complex, subunit 7 |
| Synonyms name | BTG1 binding factor 1 |
| Locus | 8p22 |
| Discovery year | 2000-12-01 |
| GenBank acession | L46722 |
| Entrez gene record | 29883 |
| Pubmed identfication | 10637334 1538749 17264152 |
| RefSeq identity | NM_013354 |
| Classification | CCR4-NOT transcription complex |
| Havana BLAST/BLAT | OTTHUMG00000096971 |