| Long name | p47 Primary Polyclonal Antibody |
| Also known as | p47 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | p47 |
| Specificity | This is a highly specific antibody against p47 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Pleckstrin/p47 |
| Gene ID number | 5341 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Functioning as part of a ternary complex with VCP (a protein involved in the heterotypic fusion of transport vesicles with their target membranes) and Syntaxin 5, Human p47 shares 89% sequence identity with its mouse counterpart, Multiple isoforms of p47 exist due to alternative splicing events, UBX1, UBXD10 or UBXN2C, also known as NSFL1C, is a 370 amino acid protein that localizes to both the nucleus and the golgi apparatus (specifically to golgi stacks) and contains one SEP domain and one UBX domain, p47 interacts with and reduces the ATPase activity of VCP and is required for the fragmentation of golgi stacks during mitosis and for subsequent reassembly of golgi stacks after mitosis, p47 is subject to phosphorylation during mitosis, required for proper golgi stack formation and cisternal regrowth, suggesting a conserved role between species, therefore, which inhibits p47-golgi interaction and is, Platelet P47 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | FLJ27168, OTTHUMP00000159962, PLEK, PLEK_HUMAN, Platelet 47 kDa protein, Platelet P47, Platelet and leukocyte C kinase substrate, Platelet p47 protein, Pleckstrin, p47 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | p47 |
| Short name | p47 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | p47 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9070 |
| Gene | PLEK |
| Long gene name | pleckstrin |
| Synonyms | P47 |
| Locus | 2p14 |
| Discovery year | 1998-04-07 |
| GenBank acession | X07743 |
| Entrez gene record | 5341 |
| Pubmed identfication | 2897630 12054651 |
| RefSeq identity | NM_002664 |
| Classification | Pleckstrin homology domain containing |
| Havana BLAST/BLAT | OTTHUMG00000129562 |
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