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PAR4 (Thr163) Antibody

PAR4 (Thr163) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePAR4 (Thr163) Primary Polyclonal Antibody
Also known asPAR4 (Thr163) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPAR4 Thr163
SpecificityThis is a highly specific antibody against PAR4 Thr163
Modification(s)Phosphorylation
Modification site(s)Thr163
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human PAR4 around the phosphorylation site of Thr163
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen 2001), 2001), 2006), However, Mice lacking PAR4 are protected from mesenteric arteriole thrombosis, PAR1 and PAR3 are activated by thrombin, PAR4 is expressed along with PAR1 on human platelets, The PAR family consists of 4 receptors, and PAR2 and PAR4 are activated by several serine proteases (Macfarlane et al, and each plays an important role in thrombin-induced platelet aggregation (Holinstat et al, and platelets from mice lacking PAR4 fail to aggregate in response to thrombin (Sambrano et al, indicating that PAR4 is a potential target for treatment of thrombosis in humans, platelets from mice express PAR4 but not PAR1, that are activated by proteolytic cleavage of the N-terminal domain of the receptor to reveal a tethered ligand, the proteinase-activated receptors (PARs), PAR4 is a member of a unique family of GPCRs
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 2310001G03Rik, PAWR, PRKC Apoptosis WT1 Regulator, PRKC apoptosis WT1 regulator protein, Par4 induced by effectors of apoptosis, Prostate apoptosis response 4 protein, Prostate apoptosis response protein 4, Prostate apoptosis response protein PAR 4, Proteinase-Activated Receptor 4, TRANSCRIPTIONAL REPRESSOR PAR4, Transcriptional repressor Par-4-like protein PAWR, WT1 Interacting Protein, protease-activated receptor 4, PAR 4
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPAR4 (Thr163)
Short namePAR4 (Thr163) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePAR4 (Thr163) (Antibody to)
Alternative techniqueantibodies
Identity 29998
Gene PWAR4
Long gene name Prader Willi/Angelman region RNA 4
Synonyms PAR4 PAR-4
Locus 15q11, 2
Discovery year 2013-06-14
Entrez gene record 347745
Pubmed identfication 11106375 7987392

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