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PGGT1A Antibody

PGGT1A Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePGGT1A Primary Polyclonal Antibody
Also known asPGGT1A PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPGGT1A
SpecificityThis is a highly specific antibody against PGGT1A
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PGGT1A/FNTA
Gene ID number2339
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen A is usually but not always an aliphatic amino acid, FNTA is also a specific cytoplasmic interactor of the transforming growth factor-beta and activin type I receptors, It is likely to be a key component of the signaling pathway which involves p21ras, This enzyme has the remarkable property of farnesylating peptides as short as four residues in length that conform to the CAAX consensus sequence, This type of posttranslational modification provides a mechanism for membrane localization of proteins that lack a transmembrane domain, also known as CAAX farnesyltransferase (FTase), an important substrate for farnesyltransferase, and X is typically methionine or serine, attaches a farnesyl group from farnesyl pyrophosphate to cysteine residues at the fourth position from the C terminus of proteins that end in the so-called CAAX box, where C is cysteine, FNTA
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CAAX box, FNTA_HUMAN, FPTA, FTase alpha, Farnesyl protein transferase alpha subunit, Farnesyltransferase, Farnesyltransferase CAAX box alpha, GGTase I alpha, PGGT1A, PTAR2, Protein farnesyltransferase/geranylgeranyltransferase type I alpha subunit, Protein prenyltransferase alpha subunit repeat containing 2, Ras proteins prenyltransferase alpha, Ras proteins prenyltransferase subunit alpha, Type I protein geranyl geranyltransferase alpha subunit, alpha, CAAX farnesyltransferase alpha subunit
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPGGT1A
Short namePGGT1A Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePGGT1A (Antibody to)
Alternative techniqueantibodies
Identity 3782
Gene FNTA
Long gene name CAAX box, alpha , farnesyltransferase
Synonyms FPTA PGGT1A PTAR2
Synonyms name protein prenyltransferase alpha subunit repeat containing 2 protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
Locus 8p11, 21
Discovery year 1993-04-08
GenBank acession L10413
Entrez gene record 2339
Pubmed identfication 8276393
RefSeq identity NM_002027
Classification Prenyltransferase alpha subunit repeat containing
Havana BLAST/BLAT OTTHUMG00000165279

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