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PTPN11 (Tyr584) Antibody

PTPN11 (Tyr584) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePTPN11 (Tyr584) Primary Polyclonal Antibody
Also known asPTPN11 (Tyr584) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPTPN11 Tyr584
Specificity This phosphorylation site is homologous across the listed cross reactive species, This is a highly specific antibody against PTPN11 Tyr584
Modification(s)Phosphorylation
Modification site(s)Tyr584
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range550-597/597
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human PTPN11 around the phosphorylation site of Tyr584
Gene ID number5781
Swiss ProtQ06124
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Dephosphorylates ROCK2 at Tyr-722 resulting in stimulatation of its RhoA binding activity, Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BPTP3, NS1, PTP-1D, PTP-2C, PTP2C, PTPN11, Protein-tyrosine phosphatase 1D, Protein-tyrosine phosphatase 2C, SH-PTP2, SH-PTP3, SHP-2, SHP2, SHPTP2, Tyrosine-protein phosphatase non-receptor type 11, CFC
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPTPN11 (Tyr584)
Short namePTPN11 (Tyr584) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePTPN11 (Tyr584) (Antibody to)
Alternative techniqueantibodies
Identity 9644
Gene PTPN11
Long gene name non-receptor type 11 , protein tyrosine phosphatase
Synonyms gene NS1
Synonyms gene name Noonan syndrome 1
Synonyms BPTP3 SH-PTP2 SHP-2 PTP2C SHP2
Locus 12q24, 13
Discovery year 1993-03-03
GenBank acession D13540
Entrez gene record 5781
Pubmed identfication 7894486 1280823
Classification Protein tyrosine phosphatases, non-receptor type SH2 domain containing
Havana BLAST/BLAT OTTHUMG00000134334
Locus Specific Databases LRG_614

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