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RAD51(Tyr315) Antibody

RAD51(Tyr315) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameRAD51(Tyr315) Primary Polyclonal Antibody
Also known asRAD51(Tyr315) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenRAD51 Tyr315
SpecificityThis is a highly specific antibody against RAD51 Tyr315
Modification(s)Phosphorylation
Modification site(s)Tyr315
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human RAD51 around the phosphorylation site of Tyr315
Gene ID number5888
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein, Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis, RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, This protein can interact with the ssDNA-binding protein RPA and RAD52, This protein is also found to interact with BRCA1 and BRCA2, Transcript variants utilizing alternative polyA signals exist, Two alternatively spliced transcript variants of this gene, and are known to be involved in the homologous recombination and repair of DNA, and it is thought to play roles in homologous pairing and strand transfer of DNA, have been reported, which encode distinct proteins, which may be important for the cellular response to DNA damage, The protein encoded by this gene is a member of the RAD51 protein family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BRCA1/BRCA2 containing complex, BRCC 5, BRCC5, DNA repair protein RAD51 homolog 1, DNA repair protein rhp51, E, E, E coli RecA homolog, HGNC:9817, HRAD51, Homolog of E coli RecA, HsRad51, HsT16930, RAD51 S cerevisiae homolog, RAD51 homolog, RAD51 homolog RecA homolog, RAD51 homolog S, RAD51A, RECA, Rad 51, RecA, RecA homolog E, RecA like protein, cerevisiae, cerevisiae, coli, coli, coli S, homolog of, homolog of S cerevisiae RAD51, recombination protein A, subunit 5, RAD51phospho Y315
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetRAD51(Tyr315)
Short nameRAD51(Tyr315) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRAD51(Tyr315) (Antibody to)
Alternative techniqueantibodies
Identity 9817
Gene RAD51
Long gene name RAD51 recombinase
Synonyms gene RAD51A RECA
Synonyms gene name E, RAD51 (S, cerevisiae) , cerevisiae) RAD51 homolog (S, cerevisiae) homolog (E coli RecA homolog) RAD51 homolog (RecA homolog, coli) (S
Synonyms HsRad51 HsT16930 BRCC5 FANCR
Synonyms name BRCA1/BRCA2-containing complex, subunit 5
Locus 15q15, 1
Discovery year 1993-05-26
GenBank acession D13804
Entrez gene record 5888
Pubmed identfication 8358431 8479919 26253028
RefSeq identity NM_002875 NM_133487
Classification Fanconi anemia complementation groups
Havana BLAST/BLAT OTTHUMG00000130067

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