Name : RNF12 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN9237952541
| Long name | RNF12 Primary Polyclonal Antibody |
| Also known as | RNF12 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | RNF12 |
| Specificity | This is a highly specific antibody against RNF12 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 550-600/624 |
| Subcellular location | Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RNF12 |
| Gene ID number | 51132 |
| Swiss Prot | Q9NVW2 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Acts as a negative coregulator for LIM homeodomain transcription factors by mediating the ubiquitination and subsequent degradation of LIM cofactors LDB1 and LDB2 and by mediating the recruitment the SIN3a/histone deacetylase corepressor complex, By targeting ZFP42 for degradation, Plays a role in telomere length-mediated growth suppression by mediating the ubiquitination and degradation of TERF1, Ubiquitination and degradation of LIM cofactors LDB1 and LDB2 allows DNA-bound LIM homeodomain transcription factors to interact with other protein partners such as RLIM, a stochastic process in which one X chromosome is inactivated to minimize sex-related dosage differences of X-encoded genes in somatic cells of female placental mammals, acts as an activator of random inactivation of X chromosome in the embryo, E3 ubiquitin-protein ligase |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | E3 ubiquitin-protein ligase RLIM, LIM domain-interacting RING finger protein, NY-REN-43, R-LIM, RING finger LIM domain-binding protein, RING finger protein 12, RLIM, Renal carcinoma antigen NY-REN-43, RNF12 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | RNF12 |
| Short name | RNF12 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | RNF12 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 13429 |
| Gene | RLIM |
| Long gene name | LIM domain interacting , ring finger protein |
| Synonyms gene | RNF12 |
| Synonyms gene name | ring finger protein 12 |
| Synonyms | NY-REN-43 MGC15161 |
| Synonyms name | ring zinc finger protein NY-REN-43antigen LIM domain interacting ring finger protein E3 ubiquitin-protein ligase RLIM |
| Locus | Xq13, 2 |
| Discovery year | 2002-04-30 |
| GenBank acession | AF155109 |
| Entrez gene record | 51132 |
| Pubmed identfication | 10508479 |
| RefSeq identity | NM_016120 |
| Classification | Ring finger proteins |
| Havana BLAST/BLAT | OTTHUMG00000021859 |
| Locus Specific Databases | Mental Retardation database |