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RNF56 Antibody

RNF56 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameRNF56 Primary Polyclonal Antibody
Also known asRNF56 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenRNF56
SpecificityThis is a highly specific antibody against RNF56
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range90-140/982
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RNF56/CBL-B
Gene ID number868
Swiss ProtQ13191
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Also acts by promoting PIK3R1/p85 ubiquitination, BCR (B-cell receptor) and FCER1 (high affinity immunoglobulin epsilon receptor) signal transduction pathways, In B-cells, In activated T-cells, In naive T-cells, May be functionally coupled with the E2 ubiquitin-protein ligase UB2D3, May be involved in EGFR ubiquitination and internalization, Negatively regulates TCR (T-cell receptor), Slightly promotes SRC ubiquitination, acts by ubiquitinating SYK and promoting its proteasomal degradation, and transfers it to substrates, generally promoting their degradation by the proteasome, inhibits PLCG1 activation and calcium mobilization upon restimulation and promotes anergy, inhibits VAV1 activation upon TCR engagement and imposes a requirement for CD28 costimulation for proliferation and IL-2 production, which impairs its recruitment to the TCR and subsequent activation, E3 ubiquitin-protein ligase which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CBLB, Casitas B-lineage lymphoma proto-oncogene b, E3 ubiquitin-protein ligase CBL-B, Nbla00127, RING finger protein 56, RNF56, SH3-binding protein CBL-B, Signal transduction protein CBL-B, Cbl-b
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetRNF56
Short nameRNF56 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRNF56 (Antibody to)
Alternative techniqueantibodies
Identity 1542
Gene CBLB
Long gene name Cbl proto-oncogene B
Synonyms gene name Cas-Br-M (murine) ectropic retroviral transforming sequence b Cas-Br-M (murine) ecotropic retroviral transforming sequence b Cbl proto-oncogene B, E3 ubiquitin protein ligase
Synonyms RNF56 Cbl-b
Locus 3q13, 11
Discovery year 1995-12-18
GenBank acession U26710
Entrez gene record 868
Pubmed identfication 7784085
RefSeq identity NM_170662
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000150654

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