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SAMHD1 Antibody

SAMHD1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSAMHD1 Primary Polyclonal Antibody
Also known asSAMHD1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSAMHD1
SpecificityThis is a highly specific antibody against SAMHD1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SAMHD1
Gene ID number4861
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen A form of Aicardi-Goutieres syndrome, Clinical features as thrombocytopenia, Death often occurs in early childhood, May play a role in mediating proinflammatory responses to TNF-alpha signaling, No expression is seen in brain and thymus, Severe neurological dysfunctions manifest in infancy as progressive microcephaly, a genetically heterogeneous disease characterized by cerebral atrophy, and negative serologic investigations for common prenatal infection, chronic cerebrospinal fluid (CSF) lymphocytosis, dystonic posturing and profound psychomotor retardation, hepatosplenomegaly and elevated hepatic transaminases along with intermittent fever may erroneously suggest an infective process, increased CSF alpha-interferon, intracranial calcifications, leukoencephalopathy, liver, lung and peripheral blood leukocytes, placenta, skeletal muscle, small intestine, spasticity, spleen, Involvement in disease:Defects in SAMHD1 are the cause of Aicardi-Goutieres syndrome type 5 (AGS5) , Putative nuclease involved in innate immune response by acting as a negative regulator of the cell-intrinsic antiviral response, Tissue specificity:Expressed in heart
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Dendritic cell derived NG induced protein, Dendritic cell-derived NG-induced protein, HD domain containing 1, HDDC1, MOP 5, MOP5, Mg11, Monocyte protein 5, OTTHUMP00000030889, SAM domain and HD domain 1, SAM domain and HD domain containing protein 1, SAM domain and HD domain-containing protein 1, SAMH1_HUMAN, SBBI88, Samhd1, DCIP
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSAMHD1
Short nameSAMHD1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSAMHD1 (Antibody to)
Alternative techniqueantibodies
Identity 15925
Gene SAMHD1
Long gene name SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
Synonyms gene name SAM domain and HD domain 1
Synonyms SBBI88 Mg11 HDDC1 MOP-5 AGS5
Synonyms name HD domain containing 1 monocyte protein 5 Aicardi-Goutieres syndrome 5
Locus 20q11, 23
Discovery year 2001-07-31
GenBank acession AF228421
Entrez gene record 25939
Pubmed identfication 11064105 11230166 22056990
RefSeq identity NM_015474
Classification Sterile alpha motif domain containing
Havana BLAST/BLAT OTTHUMG00000032402
Locus Specific Databases LRG_281

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