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SHFM3 Antibody

SHFM3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameSHFM3 Primary Polyclonal Antibody
Also known asSHFM3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenSHFM3
SpecificityThis is a highly specific antibody against SHFM3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human SHFM3
Gene ID number6468
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Likely to be involved in key signaling pathways crucial for normal limb development, May participate in Wnt signaling, SHFM3 is an autosomal dominant disorder characterized by hypoplasia/aplasia of the central digits with fusion of the remaining digits, Involvement in disease:Defects in FBXW4 are a cause of split-hand/foot malformation type 3 (SHFM3) , Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Dactylin, F box and WD 40 domain containing protein 4, F box and WD 40 domain protein 4, F box and WD repeat domain containing 4, F box/WD repeat containing protein 4, F box/WD repeat protein 4, F-box and WD-40 domain-containing protein 4, F-box/WD repeat-containing protein 4, FBW 4, FBW4, FBWD 4, FBWD4, FBXW 4, FBXW4, FBXW4_HUMAN, SHFM 3, SHSF 3, SHSF3, Split hand/foot malformation ectrodactyly type, DAC
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetSHFM3
Short nameSHFM3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameSHFM3 (Antibody to)
Alternative techniqueantibodies
Identity 10847
Gene FBXW4
Long gene name F-box and WD repeat domain containing 4
Synonyms gene SHFM3
Synonyms gene name split hand/foot malformation (ectrodactyly) type 3 F-box and WD-40 domain protein 4
Synonyms Fbw4 dactylin
Locus 10q24, 32
Discovery year 1994-09-26
GenBank acession AF281859
Entrez gene record 6468
Pubmed identfication 8723077 7912888
RefSeq identity NM_022039
Classification F-box and WD repeat domain containing WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000018938

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