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THOC2 Antibody

THOC2 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameTHOC2 Primary Polyclonal Antibody
Also known asTHOC2 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenTHOC2
SpecificityThis is a highly specific antibody against THOC2
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range130-180/1593
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human THOC2
Gene ID number57187
Swiss ProtQ8NI27
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, Required for NXF1 localization to the nuclear rim, THOC2 (and probably the THO complex) is involved in releasing mRNA from nuclear speckle domains, TREX is recruited to spliced mRNAs by a transcription-independent mechanism, The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway, processing and nuclear export, Required for efficient export of polyadenylated RNA and spliced mRNA
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CXorf3, THO complex subunit 2, THOC2, dJ506G2, hTREX120, 1, THO2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetTHOC2
Short nameTHOC2 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameTHOC2 (Antibody to)
Alternative techniqueantibodies
Identity 19073
Gene THOC2
Long gene name THO complex 2
Synonyms gene CXorf3 MRX12 MRX35
Synonyms gene name X-linked 12 mental retardation, X-linked 35 , chromosome X open reading frame 3 mental retardation
Synonyms THO2 dJ506G2, 1
Locus Xq25
Discovery year 2002-12-09
GenBank acession AF441770
Entrez gene record 57187
Pubmed identfication 11979277 15998806 26166480
Classification X-linked mental retardation THO complex
Havana BLAST/BLAT OTTHUMG00000022334
Locus Specific Databases Mental Retardation database

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