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Unc5a/UNC5H1 Antibody

Unc5a/UNC5H1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameUnc5a/UNC5H1 Primary Polyclonal Antibody
Also known asUnc5a/UNC5H1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenUnc5a/UNC5H1
SpecificityThis is a highly specific antibody against Unc5a/UNC5H1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Unc5a
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Additionally, In the absence of netrin-1, The expression of UNC5H receptors is downregulated in multiple carcinomas, This activity is blocked by the binding of netrin-1, Three isoforms of UNC5H1 exist due to alternative splicing events, UNC5H receptors act as tumor suppressors by inhibiting anchorage-independent growth and invasion, UNC5H1, also known as UNC5HA (unc-5 homolog A), breast, but mutation of these receptors provides a potential mechanism for tumorigenicity, including colorectal, is a member of the UNC5H family of proteins and is localized to the cell membrane, lung and kidney cancers, ovary, stomach, uterus, when cleaved by a caspase to produce an intracellular fragment containing a death domain, The UNC5H family of proteins act as transmembrane receptors for netrin-1 and play a crucial role in axon guidance and migration of neural cells, UNC5H receptors induce apoptosis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names FLJ16449, KIAA1976, Netrin receptor UNC5A, Netrin receptor Unc5h1, Protein unc-5 homolog 1, Protein unc-5 homolog A, UNC5A_HUMAN, Unc 5 homolog 1, Unc 5 homolog A, Unc 5a, Unc5 a, Unc5 homolog 1, Unc5 homolog A, Unc5a, Unc5h1, Netrin receptor UNC 5A
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetUnc5a/UNC5H1
Short nameUnc5a/UNC5H1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name elegans)/UNC5H1 (Antibody to), unc-5 homolog A (C
Alternative techniqueantibodies
Identity 12567
Gene UNC5A
Long gene name unc-5 netrin receptor A
Synonyms gene name elegans) , unc5 (C, elegans homolog) a unc-5 homolog A (C
Synonyms KIAA1976 UNC5H1
Locus 5q35, 2
Discovery year 1998-12-09
GenBank acession AB075856
Entrez gene record 90249
Pubmed identfication 12655055 20372800
RefSeq identity XM_030300
Classification I-set domain containing
Havana BLAST/BLAT OTTHUMG00000163225

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