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AXL (Tyr698+Tyr702+Tyr703) Antibody

AXL (Tyr698+Tyr702+Tyr703) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameAXL (Tyr698+Tyr702+Tyr703) Antibody
Also known asAXL (Tyr698+Tyr702+Tyr703) Antibody
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenAXL Tyr698+Tyr702+Tyr703
SpecificityThis is a highly specific antibody against AXL Tyr698+Tyr702+Tyr703
Modification(s)Phosphorylation
Modification site(s)Tyr698+Tyr702+Tyr703
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationCytoplasm
SourceKLH conjugated synthetic phosphopeptide derived from human AXL around the phosphorylation site of Tyr698+Tyr702+Tyr703
Gene ID number558
Tested Applications FCM, IF(IHC-P), IHC-P, WB
Recommended dilutions FCM(1:20-100), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Although it is similar to other receptor tyrosine kinases, Axl is a chronic myelogenous leukemia associated oncogene and also associated with colon cancer and melanoma, It is involved in the stimulation of cell proliferation, It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors such as vitamin K dependent protein growth arrest specific gene 6, This gene has two different alternatively spliced transcript variants (AXL1 and AXL2), This receptor can also mediate cell aggregation by homophilic binding, the Axl protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats, The Axl gene is evolutionarily conserved between vertebrate species, The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names AI323647, AXL oncogene, AXL receptor tyrosine kinase, AXL transforming gene, AXL transforming sequence/gene, Ark, Axl, EC 2, JTK11, Oncogene AXL, Tyro7, Tyrosine protein kinase receptor UFO, Tyrosine-protein kinase receptor UFO, UFO, UFO_HUMAN, 1, 7, 10, Adhesion related kinase
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetAXL (Tyr698+Tyr702+Tyr703)
Short nameAXL (Tyr698+Tyr702+Tyr703) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameAXL (Tyr698+Tyr702+Tyr703) (Antibody to)
Alternative techniqueantibodies
Identity 905
Gene AXL
Long gene name AXL receptor tyrosine kinase
Synonyms UFO JTK11 Tyro7 ARK
Locus 19q13, 2
Discovery year 1992-09-15
GenBank acession M76125
Entrez gene record 558
Pubmed identfication 1656220
Classification Immunoglobulin like domain containing V-set domain containing Fibronectin type III domain containing Receptor Tyrosine Kinases
Havana BLAST/BLAT OTTHUMG00000182727

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