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BORA Antibody

BORA Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameBORA Primary Polyclonal Antibody
Also known asBORA PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenBORA
SpecificityThis is a highly specific antibody against BORA
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human BORA
Gene ID number79866
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Bora (protein aurora borealis) is a 559 amino acid protein that activates ARK-1, Bora is localized to the nucleus until mitosis is initiated, Downregulation of the gene encoding Bora results in multipolar spindles in mitosis, It is through this mechanism that Bora and ARK-1 control cellular mitotic entry, Plk (polo-like kinase) interacts with Bora to control the accessibility of its activation loop for phosphorylation and activation on its N-terminus by ARK-1, This translocation is dependent on activated Cdc2, a phenomenon that is also observed when ARK-1 function is blocked, bipolar spindle assembly and chromosome segregation during mitosis, when it then translocates to the cytoplasm, which releases Bora to bind and activate ARK-1 in the cytoplasm, Aurora related kinase-1 (ARK-1) is a centrosome-associated serine/threonine kinase that regulates centrosome separation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BORA_HUMAN, C13orf34, Chromosome 13 open reading frame 34, FLJ22624, HsBora, Protein aurora borealis, RP11-342J4, bora, 2, Aurora borealis
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetBORA
Short nameBORA Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameBORA (Antibody to)
Alternative techniqueantibodies
Identity 24724
Gene BORA
Long gene name aurora kinase A activator , bora
Synonyms gene C13orf34
Synonyms gene name chromosome 13 open reading frame 34
Synonyms FLJ22624
Locus 13q21, 33
Discovery year 2006-08-15
GenBank acession BC025367
Entrez gene record 79866
Pubmed identfication 16890155 18378770 18566290 19487276
RefSeq identity NM_024808
Havana BLAST/BLAT OTTHUMG00000017068

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