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C2CD3 Antibody

C2CD3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameC2CD3 Primary Polyclonal Antibody
Also known asC2CD3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenC2CD3
SpecificityThis is a highly specific antibody against C2CD3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human C2CD3
Gene ID number26005
Tested Applications IF(IHC-P), IHC-P
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Atm mutation leads to the disorder known as ataxia-telangiectasia, C2 domains are regions of about 130 amino acid residues that are found in proteins that bind phospholipids, C2CD3 is expressed as five isoforms produced by alternative splicing events, It is thought that calcium binding to the C2 domain induces an electrostatic potential change that enhances phospholipid binding, Jacobsen syndrome, Jervell and Lange-Nielsen syndrome, Niemann-Pick disease, The blood disorders Sickle cell anemia and Î, The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks, The gene that encodes C2CD3 maps to human chromosome 11, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene, Wilms' tumors, also known as FLJ34770, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11, is a 2, thalassemia are caused by HBB gene mutations, which makes up around 4% of human genomic DNA, which suggests a role for the domain as an electrostatic switch, ², 353 amino acid protein that contains two C2 domains, C2CD3 (C2 domain-containing protein 3)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names C2CD3, C2CD3_HUMAN, C2 domain-containing protein 3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetC2CD3
Short nameC2CD3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameC2CD3 (Antibody to)
Alternative techniqueantibodies
Identity 24564
Gene C2CD3
Long gene name C2 calcium dependent domain containing 3
Synonyms DKFZP586P0123
Locus 11q13, 4
Discovery year 2007-10-17
GenBank acession BC035599
Entrez gene record 26005
RefSeq identity NM_015531
Classification C2 domain containing
Havana BLAST/BLAT OTTHUMG00000168110

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