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CARD14 Antibody

CARD14 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCARD14 Primary Polyclonal Antibody
Also known asCARD14 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCARD14
SpecificityThis is a highly specific antibody against CARD14
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CARD14
Gene ID number79092
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen The CARD domains of both proteins have been shown to specifically interact with BCL10, This protein is also a member of the CARD protein family, This protein shares a similar domain structure with CARD11 protein, Two alternatively spliced variants of this gene encoding distinct isoforms have been reported, When expressed in cells, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation, this protein activated NF-kappaB and induced the phosphorylation of BCL10, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD), The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Bimp 2, Bimp2, CAR14_HUMAN, CARD 14, CARD containing MAGUK 2 protein, CARD containing MAGUK protein 2, Card maguk protein 2, Carma 2, Carma2, Caspase recruitment domain containing protein 14, Caspase recruitment domain family member 14, Caspase recruitment domain protein 14, Bcl10 interacting MAGUK protein 2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCARD14
Short nameCARD14 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative name member 14 (Antibody to), caspase recruitment domain family
Alternative techniqueantibodies
Alternative to gene target CARD domain binding, CARD14 and IDBG-642674 and ENSBTAG00000015261 and 523360, CARD14 and IDBG-71483 and ENSG00000141527 and 79092, Card14 and IDBG-214692 and ENSMUSG00000013483 and 170720, Plasma membranes, member 14, this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0005515 and protein binding and molecular function this GO :0005622 and intracellular and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007250 and activation of NF-kappaB-inducing kinase activity and biological process this GO :0033209 and tumor necrosis factor-mediated signaling pathway and biological process this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0050700 and CARD domain binding and molecular function this GO :0051092 and positive regulation of NF-kappaB transcription factor activity and biological process, this GO :0005515: protein binding, this GO :0005515: protein binding and also this GO :0050700: CARD domain binding, this GO :0050700: CARD domain binding, caspase recruitment domain family
Identity 16446
Gene CARD14
Long gene name caspase recruitment domain family member 14
Synonyms gene PSORS2
Synonyms gene name member 14 , psoriasis susceptibility 2 caspase recruitment domain family
Synonyms CARMA2 BIMP2
Locus 17q25, 3
Discovery year 2002-09-19
GenBank acession AF322642
Entrez gene record 79092
Pubmed identfication 11278692 11356195 22521418
Classification Caspase recruitment domain containing Membrane associated guanylate kinases PDZ domain containing
Havana BLAST/BLAT OTTHUMG00000177549

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