Caspase-9 (Tyr153) Antibody

Caspase-9 (Tyr153) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES

Price 281

Size 0.1ml

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Long name	Caspase-9 (Tyr153) Primary Polyclonal Antibody
Also known as	Caspase-9 (Tyr153) PAb
Category	Primary Antibodies
Conjugation	Unconjugated
Target Antigen	Caspase-9 Tyr153
Specificity	This is a highly specific antibody against Caspase-9 Tyr153
Modification(s)	Phosphorylation
Modification site(s)	Tyr153
Clonality	Polyclonal antibody
Clone number	Polyclonal antibody
Concentration	1ug per 1ul
Source	KLH conjugated synthetic phosphopeptide derived from human Caspase 9 around the phosphorylation site of Tyr153
Gene ID number	842
Tested Applications	IF(IHC-P), IHC-P, WB
Recommended dilutions	IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity	Human
Cross reactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen	BclXL, Caspase 3, Caspase 9 intereacts with BIRC7 and has been shown to cleave PARP and vimentin, Caspase 9 is inhibited by the dominant negative isoform, Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6, ProCaspase 9 has been reported to be approximately 47 kD, This caspase becomes activated when recruited to Apaf1/cytochrome c complex, This caspase is active as a heterotetramer and has been reported to have two isoforms, This caspase is present in the cytosol and, XIAP, and Livin, and apoptotic protease activating factor 3 (Apaf3)) is a member of the peptidase family C14 that contains a CARD domain, and following cleavage by Apaf1, apoptotic protease Mch6, cIAP1, cIAP2, granzyme B, possibly Caspase 8 and Caspase 10 into large p37 and small p10 subunits, translocates to the mitochondria, upon activation, Caspase 9 (also known as ICE like apoptotic protease 6 (ICE LAP6)
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names	APAF3, Apoptosis related cysteine peptidase, Apoptotic protease Mch 6, Apoptotic protease activating factor 3, CASP 9, CASP9, CASP9_HUMAN, Caspase 9 Dominant Negative, Caspase 9 precursor, Caspase 9c, Caspase9, EC 3, ICE LAP6, ICE like apoptotic protease 6, MCH6 antibody RNCASP9, 4, 22, APAF 3
Properties	C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene target	Caspase-9 (Tyr153)
Short name	Caspase-9 (Tyr153) Antibody
Technique	antibodies against human proteins, antibodies for, Antibody
Alternative name	caspase-9 (Tyr153) (Antibody to)
Alternative technique	antibodies

Caspase-9 (Tyr153) Antibody

Caspase-9 (Tyr153) Antibody size: 0.1ml 281

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