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CRTAP Antibody

CRTAP Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCRTAP Primary Polyclonal Antibody
Also known asCRTAP PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCRTAP
SpecificityThis is a highly specific antibody against CRTAP
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CRTAP
Gene ID number10491
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen CRTAP forms a complex with Gros1 and CyPB (cyclophilin B) and is required for the efficient 3-hydroxylation of target prolyl residues in Collagen Type I molecules, CRTAP is widely expressed with predominant expression in articular chondrocytes, In the endoplasmic reticulum (ER), It contains a signal peptide and a tetratricopeptide-like helical domain and is essential for normal bone formation, Mutations in the gene encoding CRTAP can lead to autosomal recessive osteogenesis imperfecta (OI) type 7 and type 2B, OI, OI type 7 is a mild form of this disorder, also known as brittle bone disease, extracellular fibril assembly and intracellular trafficking, is characterized by bone fragility and susceptibility to fractures, the major structural proteins of skin and bone, while OI type 2B is a neonatal lethal condition, CRTAP is a secreted protein localizing to the extracellular space that plays a role in collagen post-translational modifications
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CASP, CRTAP_HUMAN, LEPREL3, leprecan-like 3, Cartilage associated protein
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCRTAP
Short nameCRTAP Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCRTAP (Antibody to)
Alternative techniqueantibodies
Identity 2379
Gene CRTAP
Long gene name cartilage associated protein
Synonyms CASP LEPREL3 P3H5
Synonyms name leprecan-like 3 prolyl 3-hydroxylase family member 5 (non-enzymatic)
Locus 3p22, 3
Discovery year 1999-10-19
GenBank acession AJ006470
Entrez gene record 10491
Pubmed identfication 9217321 10429950
Havana BLAST/BLAT OTTHUMG00000130746
Locus Specific Databases Osteogenesis Imperfecta Variant Database LRG_4

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