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FBXW8 Antibody

FBXW8 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameFBXW8 Primary Polyclonal Antibody
Also known asFBXW8 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenFBXW8
SpecificityThis is a highly specific antibody against FBXW8
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FBXW8/FBXO29
Gene ID number26259
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and recruitment for ubiquitination, F-box proteins are members of a large family that regulates cell cycle, FBXO29 also contains five WD repeats, FBXO29 exists as two isoforms as a result of alternative splicing events, FBXO29 is thought to recognize and bind to select phosphorylated proteins, Functioning as a component of the SCF complex, IkB-&, also designated F-box/WD repeat-containing protein 8 (FBXW8), and â, cyclin-dependent kinase inhibitors, for degradation by the proteasome after ubiquitination, immune response, is a 598 amino acid protein that contains one 40 amino acid F-box region, making it a member of the F-box family, signaling cascades and developmental programs by targeting proteins, such as cyclins, thereby promoting their ubiquitination and subsequent degradation, &circ, «, -catenin, FBXO29, aring
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names F box and WD40 domain containing protein 8, F box only protein 29, F-box only protein 29, FBW6, FBW8, FBX29, FBXO29, FBXW6, FBXW8_HUMAN, F box/WD repeat containing protein 8
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetFBXW8
Short nameFBXW8 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameFBXW8 (Antibody to)
Alternative techniqueantibodies
Identity 13597
Gene FBXW8
Long gene name F-box and WD repeat domain containing 8
Synonyms gene FBXO29
Synonyms gene name F-box only protein 29 F-box and WD-40 domain protein 8
Synonyms FBX29 FBW6 FBW8
Locus 12q24, 22
Discovery year 2000-09-27
GenBank acession AF176707
Entrez gene record 26259
Pubmed identfication 10531035 10531037
RefSeq identity NM_012174
Classification F-box and WD repeat domain containing WD repeat domain containing
Havana BLAST/BLAT OTTHUMG00000169329

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