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FLT-3 Antibody

FLT-3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameFLT-3 Primary Polyclonal Antibody
Also known asFLT-3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenFLT-3
SpecificityThis is a highly specific antibody against FLT-3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Subcellular locationCytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FLT-3
Gene ID number2322
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Activation of wild-type FLT3 causes only marginal activation of STAT5A or STAT5B, FER, Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways, PLCG1, PTPN11/SHP-2, PTPN6/SHP, Promotes activation of RAS signaling and phosphorylation of downstream kinases, Promotes phosphorylation of FES, Promotes phosphorylation of SHC1 and AKT1, and STAT5A and/or STAT5B, and activation of the downstream effector MTOR, including MAPK1/ERK2 and/or MAPK3/ERK1, proliferation and survival of hematopoietic progenitor cells and of dendritic cells, Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names FL cytokine receptor, FLT3_HUMAN, FMS like tyrosine kinase 3, Fetal liver kinase 2, Flk 2, Flk2, Flt 3, Flt3, Fms related tyrosine kinase 3, Growth factor receptor tyrosine kinase type III, Stem cell tyrosine kinase 1, Stk 1, Stk1, Tyrosine protein kinase receptor FLT3, CD135 antigen
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetFLT-3
Short nameFLT-3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameFLT-3 (Antibody to)
Alternative techniqueantibodies

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