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hHBrk1 Antibody

hHBrk1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namehHBrk1 Primary Polyclonal Antibody
Also known ashHBrk1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenhHBrk1
SpecificityThis is a highly specific antibody against hHBrk1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human hHBrk1
Gene ID number55845
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Because HSPC300 is a highly conserved subunit of the WAVE complex across many species, Free HSPC300 exists as homotrimers prior to its incorporation into the WAVE complex, Genetic depletion of HSPC300 results in cytoskeletal abnormalities and prevents cytokinesis of cells, HSPC300 is thought to be necessary for synaptic morphogenesis by motoneurons, HSPC300 is thought to localize to axons of the central nervous system of Drosophila embryos and thus may also be involved in axonogenesis, HSPC300 is thought to regulate cytoskeletal organization and Actin polymerization, In Drosophila, In addition, In mice, The WAVE complex includes five proteins, and it is therefore hypothesized that HSPC300 may also be involved in cognitive functions, it is thought to have the same or similar functions in many different organisms, one of which is HSPC300, suggesting that decreased levels of HSPC300 may be associated with tumor suppression, that regulate the ARC (Arp2/3 complex) which is responsible for Actin nucleation and is Rac 1-dependent, the WAVE/ARC pathway may affect the development of the nervous system, the knockout of the WAVE complex leads to learning and memory defects, HSPC300 (hematopoietic stem cell protein 300) is also known as probable protein BRICK1 or C3orf10 (chromosome 3 open reading frame 10) and is a 75 amino acid protein that is expressed as two isoforms and localizes to both the cytoplasm and the cytoskeleton
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names BRK1_HUMAN, C3ORF10 GENE, C3orf10 chromosome 3 open reading frame 10, Chromosome 3 open reading frame 10, HSPC300, MDS027, Probable protein BRICK1, hHBrk1, Brk1-like
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targethHBrk1
Short namehHBrk1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namehHBrk1 (Antibody to)
Alternative techniqueantibodies

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