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INTS3 Antibody

INTS3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameINTS3 Primary Polyclonal Antibody
Also known asINTS3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenINTS3
SpecificityThis is a highly specific antibody against INTS3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range960-998/1043
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human INTS3
Gene ID number65123
Swiss ProtQ68E01
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Component of the SOSS complex, In the SOSS complex, The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes, The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing, The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, The SOSS complex is required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint, it is required for the assembly of the complex and for stabilization of the complex at DNA damage sites, recombinational repair and maintenance of genomic stability, Component of the Integrator complex
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names C1orf193, C1orf60, INTS3, Integrator complex subunit 3, SOSS complex subunit A, SOSS-A, SOSSA, Sensor of single-strand DNA complex subunit A, Sensor of ssDNA subunit A, INT3
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetINTS3
Short nameINTS3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameINTS3 (Antibody to)
Alternative techniqueantibodies
Identity 26153
Gene INTS3
Long gene name integrator complex subunit 3
Synonyms gene C1orf60
Synonyms gene name chromosome 1 open reading frame 60
Synonyms FLJ21919 INT3 SOSS-A
Synonyms name sensor of single-strand DNA complex subunit A
Locus 1q21, 3
Discovery year 2005-05-13
GenBank acession BX640950
Entrez gene record 65123
Pubmed identfication 16239144
RefSeq identity NM_023015
Classification Integrator complex
Havana BLAST/BLAT OTTHUMG00000037089

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