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NALP4 Antibody

NALP4 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameNALP4 Primary Polyclonal Antibody
Also known asNALP4 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenNALP4
Specificity C and E Mouse variants, This antibody will detect multiple forms of NALP4, including the A, This is a highly specific antibody against NALP4
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range370-420/994
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NALP4
Gene ID number147945
Swiss ProtQ96MN2
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Acts as a negative regulator of the type I interferon signaling pathway by serving as an adapter to promote DTX4-mediated ubiquitination of activated TBK1, Suppresses NF-kappaB induction by the cytokines TNFA and IL1B, and its subsequent degradation, suggesting that it operates at a point of convergence in these two cytokine signaling pathways, May be involved in inflammation and recognition of cytosolic pathogen-associated molecular patterns (PAMPs) not intercepted by membrane-bound receptors
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CT58, Cancer/testis antigen 58, LRR and PYD domains-containing protein 4, NALP4, NLRP4, PAAD and NACHT-containing protein 2, PAN2, PYPAF4, PYRIN and NACHT-containing protein 2, PYRIN-containing APAF1-like protein 4, RNH2, Ribonuclease inhibitor 2, NACHT
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetNALP4
Short nameNALP4 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameNALP4 (Antibody to)
Alternative techniqueantibodies
Identity 22943
Gene NLRP4
Long gene name NLR family pyrin domain containing 4
Synonyms gene NALP4
Synonyms gene name NACHT, leucine rich repeat and PYD containing 4
Synonyms PYPAF4 FLJ32126 PAN2 RNH2 CLR19, 5 CT58
Synonyms name leucine rich repeat and pyrin domain containing 4 cancer/testis antigen 58 , nucleotide-binding oligomerization domain
Locus 19q13, 43
Discovery year 2003-10-28
GenBank acession AF479747
Entrez gene record 147945
Pubmed identfication 12563287 12019269
RefSeq identity NM_134444
Classification NLR family Pyrin domain containing
Havana BLAST/BLAT OTTHUMG00000181734

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