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ORC1L Antibody

ORC1L Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameORC1L Primary Polyclonal Antibody
Also known asORC1L PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenORC1L
SpecificityThis is a highly specific antibody against ORC1L
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ORC1L/ORC1
Gene ID number4998
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Among the proteins required for establishing these complexes are the origin recognition complex (ORC) proteins (1), Human ORC subunits 1-6 are expressed in the nucleus of proliferating cells and tissues, ORC proteins bind specifically to origins of replication where they serve as scaffold for the assembly of additional initiation factors (1), ORC1 and ORC2 are both expressed at equivalent concentrations throughout the cell cycle, ORC2, ORC3, ORC4 and ORC5 form a core complex upon which ORC6 and ORC1 assemble (7, ORC4 and ORC6 are also expressed constantly throughout the cell cycle (5, The formation of this core complex suggests that ORC proteins play a crucial role in the G1-S transition in mammalian cells (8), however, only ORC2 remains stably bound to chromatin (3, such as the testis (2), which trigger initiation (1), 4), 6), 8), The initiation of DNA replication is a multi-step process that depends on the formation of pre-replication complexes
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names MmORC1, ORC1L, ORC1_HUMAN, Origin Recognition Complex 1, Origin recognition complex, Origin recognition complex subunit 1, Origin recognition complex subunit 1 S, Origin recognition complex subunit 1 homolog, Origin recognition complex subunit 1 like, Origin recognition complex subunit 1 like S, Origin recognition complex subunit 1 yeast homolog like, PARC1, Replication control protein 1, cerevisia, cerevisiae homolog like, orc1, subunit 1 like yeast, HSORC1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetORC1L
Short nameORC1L Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameORC1L (Antibody to)
Alternative techniqueantibodies
Identity 8487
Gene ORC1
Long gene name origin recognition complex subunit 1
Synonyms gene ORC1L
Synonyms gene name cerevisiae) origin recognition complex, origin recognition complex, subunit 1 , subunit 1 (yeast homolog)-like origin recognition complex, subunit 1 homolog (S, subunit 1-like (yeast) origin recognition complex
Synonyms HSORC1 PARC1
Synonyms name S, cerevisiae, homolog-like origin recognition complex 1 replication control protein 1 , origin recognition complex, subunit 1
Locus 1p32, 3
Discovery year 1997-06-24
Entrez gene record 4998
Pubmed identfication 8884289
RefSeq identity NM_004153
Classification AAA ATPases Origin recognition complex
Havana BLAST/BLAT OTTHUMG00000008104

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