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RNF126 Antibody

RNF126 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameRNF126 Primary Polyclonal Antibody
Also known asRNF126 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenRNF126
SpecificityThis is a highly specific antibody against RNF126
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range80-130/313
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human RNF126
Gene ID number55658
Swiss ProtQ9BV68
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen By ubiquitinating CDKN1A/p21 and targeting it for degradation, Depending on the associated E2 ligase, FLT3, MET and CXCR4, May also be part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytosol are degraded by the proteasome, May also play a role in the endosomal recycling of IGF2R, May monoubiquitinate AICDA (PubMed:23277564), May provide the ubiquitin ligase activity associated with the BAG6 complex and be responsible for ubiquitination of the mislocalized proteins and their targeting to the proteasome (PubMed:24981174), Through their polyubiquitination, may also promote cell proliferation (PubMed:23026136), may play a role in the endosomal sorting and degradation of several membrane receptors including EGFR, mediates 'Lys-48'- and 'Lys-63'-linked polyubiquitination of substrates, the cation-independent mannose-6-phosphate receptor (PubMed:24275455), E3 ubiquitin-protein ligase that regulates several biological processes through ubiquitination of various target proteins
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names RING finger protein 126, RNF126, E3 ubiquitin-protein ligase RNF126
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetRNF126
Short nameRNF126 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameRNF126 (Antibody to)
Alternative techniqueantibodies
Identity 21151
Gene RNF126
Long gene name ring finger protein 126
Synonyms FLJ20552
Locus 19p13, 3
Discovery year 2003-05-21
GenBank acession BC025374
Entrez gene record 55658
RefSeq identity NM_017876
Classification Ring finger proteins
Havana BLAST/BLAT OTTHUMG00000180592

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