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ROBLD3 Antibody

ROBLD3 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameROBLD3 Primary Polyclonal Antibody
Also known asROBLD3 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenROBLD3
SpecificityThis is a highly specific antibody against ROBLD3
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ROBLD3
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Early research suggests the MP1-MAPBPIP-MEK-1 signaling complex may be critical in the regulation of tissue homeostasis, Growth factor induced MAP kinase activation is selectively mediated by the extracellular signal-regulated kinase (ERK) cascade, Knockdown of the individual proteins in the MP1/MAPBPIP complex resulted in decreased expression of the partner proteins which implies greater stability of the heterodimeric complex than either MP1 or MAPBPIP individually, MAPBPIP (mitogen-activated protein-binding protein-interacting protein), MAPBPIP compels the recruitment of MP1 to late endosomes where they form a very stable heterodimeric complex required for ERK activation on endosomes, Partner proteins MAPBPIP and MP1 are structurally almost identical each with a five-stranded â, also known as p14 and late endosomal/lysosomal MP1-interacting protein, functions as an adaptor protein augmenting the regulation of the MAP kinase cascade, &circ, «, -sheet flanked between a two-helix and one-helix layer, MP1 (MEK partner 1) functions as a scaffolding protein in the mitogen activated protein (MAP) kinase signaling pathway
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Endosomal adaptor protein p14, HSPC003, LAMTOR2, LTOR2_HUMAN, Late endosomal/lysosomal Mp1 interacting protein, Late endosomal/lysosomal Mp1-interacting protein, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2, MAPBPIP, MAPKSP1 adaptor protein, MAPKSP1AP, Mitogen activated protein binding protein interacting protein, Mitogen-activated protein-binding protein-interacting protein, ROBLD 3, RP11 336K24, Ragulator complex protein LAMTOR2, Ragulator2, Roadblock domain containing 3, Roadblock domain containing protein 3, Roadblock domain-containing protein 3, p14, 9, ENDAP
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetROBLD3
Short nameROBLD3 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameROBLD3 (Antibody to)
Alternative techniqueantibodies
Identity 29796
Gene LAMTOR2
Long gene name MAPK and MTOR activator 2 , late endosomal/lysosomal adaptor
Synonyms gene ROBLD3
Synonyms gene name roadblock domain containing 3
Synonyms MAPBPIP MAPKSP1AP p14 ENDAP Ragulator2
Synonyms name mitogen activated protein binding protein interacting protein MAPKSP1 adaptor protein endosomal adaptor protein
Locus 1q22
Discovery year 2008-09-16
GenBank acession BC024190
Entrez gene record 28956
Pubmed identfication 11042152
RefSeq identity NM_014017
Classification Ragulator complex
Havana BLAST/BLAT OTTHUMG00000017462
Locus Specific Databases MAPBPIPbase: Mutation registry for endosomal adaptor protein p14 deficiency LRG_81

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