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CYP2R1 Antibody

CYP2R1 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameCYP2R1 Primary Polyclonal Antibody
Also known asCYP2R1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenCYP2R1
SpecificityThis is a highly specific antibody against CYP2R1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CYP2R1
Gene ID number120227
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen First described in patients who had rickets at a young age despite a history of adequate vitamin D intake, The cytochrome P450 proteins are mono-oxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, The patients sera had low calcium concentrations, This enzyme is a microsomal vitamin D hydroxylase that converts vitamin D into the active ligand for the vitamin D receptor, also known as pseudovitamin D(3) deficiency rickets due to 25-hydroxylase deficiency, elevated alkaline phosphatase activity and low levels of 25-hydroxyvitamin D, low phosphate concentrations, steroids and other lipids, CYP2R1 is a member of the cytochrome P450 superfamily of enzymes, Defects in CYP2R1 are a cause of 25-hydroxyvitamin D(3) deficiency
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Cytochrome P450 family 2 R1, Cytochrome P450 family 2 subfamily R polypeptide 1, EC 1, MGC4663, Vitamin D 25 hydroxylase, 13, 14, 15, Cytochrome P450 2R1
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetCYP2R1
Short nameCYP2R1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameCYP2R1 (Antibody to)
Alternative techniqueantibodies
Identity 20580
Gene CYP2R1
Long gene name cytochrome P450 family 2 subfamily R member 1
Synonyms gene name cytochrome P450, family 2, polypeptide 1 , subfamily R
Locus 11p15, 2
Discovery year 2004-03-11
GenBank acession AY323817
Entrez gene record 120227
Pubmed identfication 12464240 12867411
RefSeq identity NM_024514
Classification Cytochrome P450 family 2
Havana BLAST/BLAT OTTHUMG00000165900
Locus Specific Databases Human Cytochrome P450 (CYP) Allele Nomenclature Committee

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