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P21 Antibody

P21 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameP21 Primary Polyclonal Antibody
Also known asP21 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenP21
SpecificityThis is a highly specific antibody against P21
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range13-41/164
Subcellular location Nucleus, Cytoplasm
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human P21
Gene ID number1026
Swiss ProtP38936
Tested Applications IF(ICC), IF(IHC-P), IHC-P, WB
Recommended dilutions IF(ICC)(1:50-200), IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen At higher stoichiometric ratios, Binds to and inhibits cyclin-dependent kinase activity, Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1, inhibits the kinase activity of the cyclin D-CDK4 complex, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression, May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CAP2, CDK-interacting protein 1, CDKN1, CDKN1A, CIP1, Cyclin-dependent kinase inhibitor 1, MDA-6, MDA6, Melanoma differentiation-associated protein 6, PIC1, SDI1, WAF1, p21CIP1, P21
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetP21
Short nameP21 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameP21 (Antibody to)
Alternative techniqueantibodies
Identity 11616
Gene TCEAL1
Long gene name transcription elongation factor A like 1
Synonyms gene name transcription elongation factor A (SII)-like 1
Synonyms p21 pp21 SIIR P21 WEX9
Locus Xq22, 2
Discovery year 1998-09-21
GenBank acession M99701
Entrez gene record 9338
Pubmed identfication 8206389 7971997 16221301
RefSeq identity NM_004780
Classification Transcription elongation factor A like family
Havana BLAST/BLAT OTTHUMG00000022699

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