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CD45

CD45 size: 100ug 321

Supplier MBS MONO
Price 321
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD45
Other names C, CD45 antigen, CD_antigen: CD45, L-CA, Leukocyte common antigen, Receptor-type tyrosine-protein phosphatase C, T200, T200 glycoprotein, T200 leukocyte common antigen, c polypeptide, protein tyrosine phosphatase, protein tyrosine phosphatase, receptor type, receptor type, receptor-type tyrosine-protein phosphatase C, receptor-type tyrosine-protein phosphatase C isoform 1
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene namePTPRC
Gene name synonimsN/A
Other gene names B220, CD45, CD45, CD45R, GP180, L-CA, L-CA, LCA, LY5, PTPRC, T200, PTPRC
ClonalityMonoclonal
Immunoglobulin isotype kappa, IgG1
Clone2B11
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity 5, Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms, CD45R functions as a phosphor-tyrosine phosphatase, CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out), Multiple isoforms of CD45R are distributed throughout the immune system according to cell type, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), The variation in these isoforms is localized to the extracellular domain of CD45R, These isoforms arise because of alternative splicing of exons 4, This particular antibody might cross react with speacies outside of the listed ones, also designated CD45 and PTPRC, and 6, broadly expressed among hematopoietic cells, has been identified as a transmembrane glycoprotein, while the intracellular domain is conserved, CD45R
Purification methodN/A
Form/AppearanceN/A
ConcentrationN/A
Storage and shipping Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C
Tested applications: Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), Western Blot (WB), Flow Cytometry (FC/FACS)
Gene targetCD45
Short nameCD45
Alternative nameCD45
Identity 9666
Gene PTPRC
Long gene name protein tyrosine phosphatase, receptor type C
Synonyms gene CD45
Synonyms LCA T200 GP180
Locus 1q31, 1 , 3-q32
Discovery year 1986-01-01
GenBank acession Y00062
Entrez gene record 5788
Pubmed identfication 2169617
RefSeq identity NM_002838
Classification Fibronectin type III domain containing CD molecules Protein tyrosine phosphatases, receptor type
Havana BLAST/BLAT OTTHUMG00000035702
Locus Specific Databases PTPRCbase: Mutation registry for CD45 deficiency LRG_95

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