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CD2

CD2 size: 100ug 354

Supplier MBS MONO
Price 354
Size 100ug
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Also known asCD2
Other names CD2 antigen (p50), CD2 molecule, CD_antigen: CD2, Erythrocyte receptor, LFA-2, LFA-3 receptor, LFA-3 receptor, Rosette receptor, T-cell surface antigen CD2, T-cell surface antigen CD2, T-cell surface antigen T11/Leu-5, T-cell surface antigen T11/Leu-5, erythrocyte receptor, lymphocyte-function antigen-2, rosette receptor, sheep red blood cell receptor, T-cell surface antigen CD2
CategoryAntibodies
SubcategoryMnoclonal antibodies
Gene nameCD2
Gene name synonimsN/A
Other gene names CD2, LFA-2, SRBC, SRBC, T11, CD2
ClonalityMonoclonal
Immunoglobulin isotype kappa, IgG2b
CloneBH1
Host organismMouse (Mus musculus)
Species reactivity Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby, Human (Homo sapiens)
Specificity and cross-reactivity CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, CD2/CD58 binding can enhance antigen-specific T cell activation, CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, NK cells and thymocytes, Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited, This particular antibody might cross react with speacies outside of the listed ones, as well as between cytolytic effectors and target cells, including endothelium, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion
Purification methodN/A
Form/AppearanceN/A
ConcentrationN/A
Storage and shipping Antibody is stable for 24 months, Temperature variations in the range of 1 to 7 degrees Celsius are tolerable, We recommend NOT to freeze the antibody, Store the antibody at +4C
Tested applications: Flow Cytometry (FC/FACS), Functional Studies, Immunofluorescence (IF), Immunohistology (IH), Immunoprecipitation (IP), ELISA (EIA)
Gene targetCD2
Short nameCD2
Alternative nameCD2 molecule
Alternative to gene target CD2 and IDBG-101417 and ENSG00000116824 and 914, CD2 and IDBG-634458 and ENSBTAG00000017256 and 497022, Cd2 and IDBG-179684 and ENSMUSG00000027863 and 12481, Extracellular, LFA-2 and SRBC and T11, protein homodimerization activity, this GO :0001766 and membrane raft polarization and biological process this GO :0004872 and receptor activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005576 and extracellular region and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006915 and apoptotic process and biological process this GO :0007155 and cell adhesion and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0007596 and blood coagulation and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009898 and cytoplasmic side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016337 and single organismal cell-cell adhesion and biological process this GO :0030101 and natural killer cell activation and biological process this GO :0030887 and positive regulation of myeloid dendritic cell activation and biological process this GO :0032760 and positive regulation of tumor necrosis factor production and biological process this GO :0034113 and heterotypic cell-cell adhesion and biological process this GO :0042110 and T cell activation and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0045580 and regulation of T cell differentiation and biological process this GO :0046658 and anchored component of plasma membrane and cellular component this GO :0050900 and leukocyte migration and biological process this GO :1902715 and positive regulation of interferon-gamma secretion and biological process this GO :2000484 and positive regulation of interleukin-8 secretion and biological process, this GO :0004872: receptor activity, this GO :0004872: receptor activity and also this GO :0005102: receptor binding and also this GO :0005515: protein binding and also this GO :0042803: protein homodimerization activity, this GO :0005102: receptor binding, this GO :0005515: protein binding, this GO :0042803: protein homodimerization activity, CD2 molecule
Identity 1639
Gene CD2
Long gene name CD2 molecule
Synonyms gene SRBC
Synonyms gene name CD2 antigen (p50), sheep red blood cell receptor
Locus 1p13, 1
Discovery year 1986-01-01
GenBank acession BC033583
Entrez gene record 914
Pubmed identfication 2437578
RefSeq identity NM_001767
Classification C2-set domain containing CD molecules V-set domain containing
Havana BLAST/BLAT OTTHUMG00000022750

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